The 2006–07 Serie C1 was the twenty-ninth edition of Serie C1, the third highest league in the Italian football league system. It was divided into two phases: the regular season, played from 3 September 2006, to 13 May 2007, and the playoff phase. Once the regular season was over teams placed 2nd to 5th entered a playoff to determine the second team in each division to be promoted to Serie B. At the same time, teams placed 14th to 17th entered a playout for the right to remain in Serie C1 the following season.