The 2008 Coca-Cola 600, the 49th running of the event, was a NASCAR stock car race held on May 25, 2008, at Lowe's Motor Speedway in Concord, North Carolina. The race was the twelfth stock car race of the 2008 NASCAR Sprint Cup season. The 400-lap race was won by Kasey Kahne of the Gillett Evernham Motorsports team, who started from the 2nd position. Greg Biffle finished second and Kyle Busch came in third.