The 2012 CAF Champions League knock-out stage matches took place between October and November 2012. The matches were held from 5–7 October (semifinals first leg), 19–21 October (semifinals second leg), 2–4 November (final first leg) and 16–18 November (final second leg). All knock-out ties were decided over two legs, with aggregate goals used to determine the winner. If the sides were level on aggregate after the second leg, the away goals rule applied, and if still level, the tie proceeded directly to a penalty shootout (no extra time is played).