The 2016 William & Mary Tribe football team represented the College of William & Mary as a member of the Colonial Athletic Association (CAA) in the 2016 NCAA Division I FCS football season. The Tribe were led by 37th-year head coach Jimmye Laycock and the team played their home games at Zable Stadium. They finished the season 5–6 overall and 3–5 in CAA play to tie for eighth place.