The 2017–18 Oklahoma Sooners women's basketball team represented the University of Oklahoma in the 2017–18 NCAA Division I women's basketball season. The Sooners were led by Sherri Coale in her twenty-second season. The team played its home games at the Lloyd Noble Center in Norman, Oklahoma as a member of the Big 12 Conference. They finished the season 16–15, 11–7 in Big 12 play to finish in a tie for third place. They lost in the quarterfinals of the Big 12 women's tournament to TCU. They received at-large bid of the NCAA women's tournament where they lost to DePaul in the first round.