The 2018 Charlotte 49ers football team represented the University of North Carolina at Charlotte in the 2018 NCAA Division I FBS football season. The 49ers played their home games at Jerry Richardson Stadium in Charlotte, NC, and competed in the East Division of Conference USA (C–USA). They were led by sixth-year head coach Brad Lambert. They finished the season 5–7, 4–4 in C-USA play to finish in fourth place in the East Division. On December 5, Charlotte hired Austin Peay head coach Will Healy for the job.