The 2021–22 season was Morecambe's 98th season since formation, their 15th consecutive season in the Football League, and their first ever season in League One, the third tier of English football. They also competed in the FA Cup, EFL Cup and EFL Trophy. During pre-season, Stephen Robinson was announced as the club's new manager on a three-year deal, succeeding Derek Adams who had departed to manage Bradford City.