The 2021–22 Western Carolina Catamounts men's basketball team represented Western Carolina University in the 2021–22 NCAA Division I men's basketball season. The Catamounts, led by first-year head coach Justin Gray, played their home games at the Ramsey Center in Cullowhee, North Carolina, as members of the Southern Conference. They finished the season 11–21, 5–13 in SoCon play to finish in last place. They lost to Mercer in the first round of the SoCon tournament.