The 2021 NCAA Division I Softball season, play of college softball in the United States organized by the National Collegiate Athletic Association (NCAA) at the Division I level, began in February 2021. The season progressed through the regular season, many conference tournaments and championship series, and concluded with the 2021 NCAA Division I softball tournament and 2021 Women's College World Series. The Women's College World Series, consisted of the eight remaining teams in the NCAA Tournament was held in Oklahoma City at USA Softball Hall of Fame Stadium, and ended on June 10, 2021.