The 2021 ToyotaCare 250 was the 6th stock car race of the 2021 NASCAR Camping World Truck Series, and the 13th iteration of the event. The race was held on Saturday, April 17, 2021 in Richmond, Virginia at Richmond Raceway, a 0.75 miles (1.21 km) permanent D-shaped oval. The race took 250 laps to complete. John Hunter Nemechek of Kyle Busch Motorsports would win the race, his 8th overall career win and his 2nd of the season. Kyle Busch of Kyle Busch Motorsports and Tyler Ankrum of GMS Racing would score the rest of the podium positions, finishing 2nd and 3rd, respectively.