The 2021 U.S. Senior Women's Open was the third U.S. Senior Women's Open. It was a professional golf tournament organized by the United States Golf Association, open to women over 50 years of age. The championship was played at the Brooklawn Country Club, Fairfield, Connecticut, United States, from July 29 to August 1 and won by Annika Sörenstam. The 2020 championship was canceled due to health concerns stemming from the COVID-19 pandemic.