The 2022 Joe McDonagh Cup is the fifth staging of the Joe McDonagh Cup since its establishment by the Gaelic Athletic Association in 2018. The fixtures were published in December 2021. Westmeath, winner of the 2021 final, were promoted to the Leinster Senior Hurling Championship, replaced by Antrim who were relegated back to this competition. Offaly were promoted from the Christy Ring Cup.