The 369th Regiment Armory is a historic National Guard Armory building located at 2366 Fifth Avenue, between West 142nd and 143rd Streets, in Harlem, Manhattan, New York City. It was built for the 369th Regiment, also known as the "Harlem Hell Fighters", founded in 1913 as the first National Guard unit in New York State composed solely of African-Americans. It later became home to the 369th Sustainment Brigade.