The 395th Tactical Missile Squadron is a United States Air Force unit. It has not been active under that name. The squadron's first predecessor was activated as the 5th Reconnaissance Squadron as the United States Army Air Corps was expanding prior to the entry of the United States into World War II. The squadron moved to Panama as the 395th Bombardment Squadron and participated in the antisubmarine campaign in the Caribbean Sea until 1943. It moved back to the United States to convert to a Boeing B-29 Superfortress unit and deployed to the China-Burma-India Theater, where it earned a Distinguished Unit Citation before it was disbanded when the Army Air Forces reorganized its very heavy bomber units from four to three squadrons.