The American Tobacco Historic District is a historic tobacco factory complex and national historic district located in Durham, Durham County, North Carolina. The district encompasses 14 contributing buildings and three contributing structures built by the American Tobacco Company and its predecessors and successors from 1874 to the 1950s. Located in the district is the separately listed Italianate style W. T. Blackwell and Company building (1874-1880, c. 1904). Other notable contributing resources are the Romanesque Revival style Hill Warehouse (1900), Washington Warehouse (1902–07), the Lucky Strike Building (1901–02), and Reed Warehouse; Noell Building (c. 1930); Power Plant and Engine House (1929–39); and the Art Moderne style Fowler (1939) Strickland (1946) and Crowe (1953) buildings.