4-amino-4-deoxychorismate lyase (EC 4.1.3.38) is an enzyme that participates in folate biosynthesis by catalyzing the production of PABA by the following reaction 4-amino-4-deoxychorismate 4-aminobenzoate + pyruvate This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. This enzyme, encoded by the pabC gene in bacteria and plants, is also known as PabC or ADC lyase. The fungal enzyme has been designated ABZ2. All known examples of 4-amino-4-deoxychorismate lyase bind PLP (pyridoxal-5'-phosphate), a cofactor employed during catalysis.
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| - Aminodeoxychorismate lyase (en)
- アミノデオキシコリスミ酸リアーゼ (ja)
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| - 4-amino-4-deoxychorismate lyase (EC 4.1.3.38) is an enzyme that participates in folate biosynthesis by catalyzing the production of PABA by the following reaction 4-amino-4-deoxychorismate 4-aminobenzoate + pyruvate This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. This enzyme, encoded by the pabC gene in bacteria and plants, is also known as PabC or ADC lyase. The fungal enzyme has been designated ABZ2. All known examples of 4-amino-4-deoxychorismate lyase bind PLP (pyridoxal-5'-phosphate), a cofactor employed during catalysis. (en)
- アミノデオキシコリスミ酸リアーゼ(Aminodeoxychorismate lyase、EC 4.1.3.38)、以下の化学反応を触媒する酵素である。 4-アミノ-4-デオキシコリスミ酸4-アミノ安息香酸 + ピルビン酸 従って、この酵素の基質はのみ、生成物は4-アミノ安息香酸とピルビン酸の2つである。 この酵素はリアーゼ、特に炭素-炭素結合を切断するオキソ酸リアーゼに分類される。系統名は、4-アミノ-4-デオキシコリスミ酸 ピルビン酸リアーゼ (4-アミノ安息香酸形成)(4-amino-4-deoxychorismate pyruvate-lyase (4-aminobenzoate-forming))である。他に、enzyme X、4-amino-4-deoxychorismate lyase、4-amino-4-deoxychorismate pyruvate-lyase等とも呼ばれる。この酵素は、葉酸の生合成に関与している。 (ja)
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| - 4-amino-4-deoxychorismate lyase (en)
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| - 4-amino-4-deoxychorismate lyase (EC 4.1.3.38) is an enzyme that participates in folate biosynthesis by catalyzing the production of PABA by the following reaction 4-amino-4-deoxychorismate 4-aminobenzoate + pyruvate This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. This enzyme, encoded by the pabC gene in bacteria and plants, is also known as PabC or ADC lyase. The fungal enzyme has been designated ABZ2. All known examples of 4-amino-4-deoxychorismate lyase bind PLP (pyridoxal-5'-phosphate), a cofactor employed during catalysis. (en)
- アミノデオキシコリスミ酸リアーゼ(Aminodeoxychorismate lyase、EC 4.1.3.38)、以下の化学反応を触媒する酵素である。 4-アミノ-4-デオキシコリスミ酸4-アミノ安息香酸 + ピルビン酸 従って、この酵素の基質はのみ、生成物は4-アミノ安息香酸とピルビン酸の2つである。 この酵素はリアーゼ、特に炭素-炭素結合を切断するオキソ酸リアーゼに分類される。系統名は、4-アミノ-4-デオキシコリスミ酸 ピルビン酸リアーゼ (4-アミノ安息香酸形成)(4-amino-4-deoxychorismate pyruvate-lyase (4-aminobenzoate-forming))である。他に、enzyme X、4-amino-4-deoxychorismate lyase、4-amino-4-deoxychorismate pyruvate-lyase等とも呼ばれる。この酵素は、葉酸の生合成に関与している。 (ja)
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