Annibale Mazzuoli (Siena, 1658 – Rome, 17 December 1743) was an Italian painter. He was born to a pedigree of artists. His father was the architect . His brothers include sculptors Giuseppe Mazzuoli and ; architect ; and the wood-carver . The sculptor, , was his nephew, and the son of Antonio Giovanni. Annibale began his career in Siena, and is described by Luigi Lanzi as a fresco painter of rapid execution, but little merit.