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About: Azimilide     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : umbel-rc:DrugProduct, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substanceDrugyago:WikicatAntiarrhythmicAgentsyago:WikicatMolecularFormulasyago:Abstraction100002137yago:Agent109190918yago:Agent114778436yago:Anticonvulsant102718469yago:CausalAgent100007347yago:Communication100033020yago:Drug103247620yago:Formula106816935yago:Hydantoin103550533yago:Matter100020827yago:Medicine103740161yago:Message106598915yago:MolecularFormula106817173yago:PhysicalEntity100001930yago:Piperazine103946814yago:WikicatHydantoinsdrugyago:Statement106722453yago:Substance100020090yago:Vermifuge104528630yago:WikicatDrugsyago:WikicatPiperazinesumbel-rc:DrugProduct New Facet based on Instances of this Class

Azimilide is a class ΙΙΙ antiarrhythmic drug (used to control abnormal heart rhythms). The agents from this heterogeneous group have an effect on the repolarization, they prolong the duration of the action potential and the refractory period. Also they slow down the spontaneous discharge frequency of automatic pacemakers by depressing the slope of diastolic depolarization. They shift the threshold towards zero or hyperpolarize the membrane potential. Although each agent has its own properties and will have thus a different function.