Belle L. Pettigrew (April 8, 1839 – July 14, 1912) was an American educator and missionary. She was a member of the Daughters of the American Revolution and the Anti-Saloon League. She served as head of the missionary and training department of the Woman's American Baptist Home Mission Society, and as South Dakota State superintendent of the press department for the Woman's Christian Temperance Union (W.C.T.U.). Hailing from Vermont, she traveled extensively around the world and lived in many cities in the United States before settling, like her brother Richard, a United States Senator, in Sioux Falls, South Dakota, where she died.