Bose Omolayo (born 1 February 1989) is a Nigerian powerlifter. She won the gold medal in the women's 79 kg event at the 2020 Summer Paralympics held in Tokyo, Japan. A few months later, she won the gold medal in her event at the 2021 World Para Powerlifting Championships held in Tbilisi, Georgia. At this event, she also set a new world record of 144 kg. She competed in the women's +61 kg event at the 2014 Commonwealth Games where she won a silver medal.