Cambarus zophanastes, also known as the Hell Creek Cave Crayfish, is named for its original location of discovery, Hell Creek Cave. It is also found in other similar habitats in Stone County and Marion County, Arkansas. These habitats include springs and caves such as Nesbitt Spring Cave in Stone County. C. zophanastes is critically endangered according to the IUCN (International Union for Conservation of Nature). C. zophanastes is also protected by the ESA (Endangered Species Act) as an endangered species. Currently conservation efforts focus on monitoring populations, reducing disturbances, and monitoring water quality. More research has to be conducted to better understand and conserve the species.