Carbondale station is an Amtrak intercity train station in Carbondale, Illinois, United States. The southern terminus of Amtrak's Illini and Saluki routes, it is also served by the City of New Orleans. Amtrak Thruway Motorcoach service between Carbondale and St. Louis, Missouri connects with the City of New Orleans. Carbondale is the southernmost Amtrak station in Illinois.