Carlos Alberto Guajardo Romero (c. 1973 – November 5, 2010) was a Mexican journalist and crime reporter who worked for the local newspaper in the border city of Matamoros, Tamaulipas. While covering a shootout between drug traffickers of the Gulf Cartel and the Mexican Army in the streets of Matamoros on 5 November 2010, Guajardo Romero was caught in the crossfire and killed. His pickup was shot more than 20 times, reportedly by military officers who mistook him for one of the drug traffickers involved in the gunfight. Guajardo Romero had left home earlier that day to cover the military-led operation targeting Antonio Cárdenas Guillén, one of Mexico's most-wanted drug lords, who was killed that afternoon.