Carmen de Luna Villajuan (16 July 1873 – 4 November 1962) was a Filipina educator and co-founded the Centro Escolar University. After completing her own education to train as a teacher, de Luna taught at the private school run by Librada Avelino in Manila and the Pandacan Public Girls' School. In 1907, the two women, along with Fernando Salas founded the Centro Escolar de Señoritas, as a non-sectarian educational facility for girls. Acting as assistant director from 1907 to 1934, she assumed the directorship upon Avelido's death and led the university until her own death in 1962.