Charles William Penrose (4 February 1832 – 16 May 1925) was a member of the Quorum of the Twelve Apostles of the Church of Jesus Christ of Latter-day Saints (LDS Church) from 1904 to 1911. Penrose was also a member of the First Presidency, serving as a counselor to church presidents Joseph F. Smith and Heber J. Grant from 1911 until his death.