Colt .45 (also known as The Colt Cousins) is an American Western series, originally starring Wayde Preston, which aired on ABC between October 1957 and September 1960. The half-hour program is loosely based on the 1950 Warner Bros. film of the same name, starring Randolph Scott. Colt .45 was part of the William T. Orr-produced array of Westerns that Warner produced for ABC in the late 1950s and early 1960s.