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About: Complement component 7     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : umbel-rc:ProteinMolecule, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: ThingBiomoleculegeneBiomoleculeGeneyago:Abstraction100002137yago:Arrangement107938773yago:Gene105436752yago:Group100031264yago:Ordering108456993yago:WikicatGenesOnChromosome5HumanGeneproteinyago:Sequence108459252yago:Series108457976umbel-rc:ProteinMolecule New Facet based on Instances of this Class

Complement component 7 is a protein involved in the complement system of the innate immune system. C7 is part of the membrane attack complex (MAC) which creates a hole on pathogen surfaces, leading to cell lysis and death. Its primary task is to bind the C5bC6 complex together. This junction alters the configuration of the protein molecules, exposing a hydrophobic site on C7 that allows the C7 to insert into the phospholipid bilayer of the pathogen.