About: Conidiobolomycosis

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Conidiobolomycosis is a rare long-term fungal infection that is typically found just under the skin of the nose, sinuses, cheeks and upper lips. It may present with a nose bleed or a blocked or runny nose. Typically there is a firm painless swelling which can slowly extend to the nasal bridge and eyes, sometimes causing facial disfigurement. The condition occurs more frequently in adults working or living in the tropical forests of South and Central America, West Africa and Southeast Asia. Males are affected more than females. The first case in a human was described in Jamaica in 1965.

Attributes	Values
rdf:type	Thing Disease yago:Abstraction100002137 yago:Attribute100024264 yago:Condition113920835 yago:Disease114070360 yago:IllHealth114052046 yago:Illness114061805 yago:PathologicalState114051917 yago:PhysicalCondition114034177 disease yago:State100024720 umbel-rc:AilmentCondition
rdfs:label	Conidiobolomycosis (en)
rdfs:comment	Conidiobolomycosis is a rare long-term fungal infection that is typically found just under the skin of the nose, sinuses, cheeks and upper lips. It may present with a nose bleed or a blocked or runny nose. Typically there is a firm painless swelling which can slowly extend to the nasal bridge and eyes, sometimes causing facial disfigurement. The condition occurs more frequently in adults working or living in the tropical forests of South and Central America, West Africa and Southeast Asia. Males are affected more than females. The first case in a human was described in Jamaica in 1965. (en)
foaf:name	Conidiobolomycosis (en)
name	Conidiobolomycosis (en)
foaf:depiction
dcterms:subject	Animal fungal diseases Fungal diseases
Wikipage page ID	9299508 (xsd:integer)
Wikipage revision ID	1104187255 (xsd:integer)
Link from a Wikipage to another Wikipage	Potassium iodide Biopsy Inhalation Medical imaging Genus Nodule (medicine) Eosinophil Morbidity Conidiobolus Conidiobolus coronatus Conidiobolus incongruus Lymphoma Subcutaneous tissue Cellulitis Amphotericin B Animal fungal diseases Basidiobolomycosis Paranasal sinuses Chronic condition Nasal congestion Itraconazole Fungal diseases Soft-tissue sarcoma Hyphae Antifungals Microscopy Sinusitis Infectious disease (medical speciality) Immunodeficiency Rhinoscleroma Mucormycosis Rhinorrhea Mycoses Entomophthoromycosis Triazoles Chronic disease Surgical debridement Nose bleed Inhaling Insect bite CT scanning
sameAs	Conidiobolomycosis Conidiobolomycosis Conidiobolomycosis
dbp:wikiPageUsesTemplate	dbt:Infobox_medical_condition_(new) dbt:Medical_resources dbt:Reflist dbt:Short_description dbt:Mycoses
thumbnail	wiki-commons:Special:FilePath/Conidiobolus_coronatus_(10.3897-mycokeys.66.46575)_Figure_4.jpg?width=300
deaths	Rare (en)
diagnosis	Medical imaging, biopsy, microscopy, culture (en)
DiseasesDB	33791 (xsd:integer)
ICD	117.700000 (xsd:double) (en) B46.8 (en)
onset	Slowly progressive (en)
symptoms	Firm painless swelling in nose, sinuses, cheeks and upper lips, blocked nose, runny nose, nose bleed (en)
treatment	Antifungals Surgical debridement
caption	Conidiobolus coronatus (en)
causes	fungi of the genus Conidiobolus (en)
duration	Chronic disease
field	Infectious disease (medical speciality)
frequency	Rare, M>F adults>children (en)
synonyms	Rhinoentomophthoromycosis (en)
has abstract	Conidiobolomycosis is a rare long-term fungal infection that is typically found just under the skin of the nose, sinuses, cheeks and upper lips. It may present with a nose bleed or a blocked or runny nose. Typically there is a firm painless swelling which can slowly extend to the nasal bridge and eyes, sometimes causing facial disfigurement. Most cases are caused by Conidiobolus coronatus, a fungus found in soil and in the environment in general, which can infect healthy people. It is usually acquired by inhaling the spores of the fungus, but can be by direct infection through a cut in the skin such as an insect bite. The extent of disease may be seen using medical imaging such as CT scanning of the nose and sinus. Diagnosis may be confirmed by biopsy, microscopy, culture and histopathology. Treatment is with long courses of antifungals and sometimes cutting out infected tissue. The condition has a good response to antifungal treatment, but can recur. The infection is rarely fatal. The condition occurs more frequently in adults working or living in the tropical forests of South and Central America, West Africa and Southeast Asia. Males are affected more than females. The first case in a human was described in Jamaica in 1965. (en)
complications	Facial disfigurement, partial or full blindness. Severe disseminated disease if weak immune system (en)
differential	Soft-tissue sarcoma Mucormycosis
medication	oral Itraconazole, topical Potassium iodide Severe disease: intravenous Amphotericin B (en)
prognosis	Longterm morbidity: facial disfigurement, good response to treatment (en)
medical cause	Genus
medication	Potassium iodide Itraconazole
symptoms	Paranasal sinuses Nasal congestion Rhinorrhea

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