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About: Donath–Landsteiner hemolytic anemia     Goto   Sponge   NotDistinct   Permalink

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Donath–Landsteiner hemolytic anemia (DLHA) is a result of cold-reacting antibody immunoglobulin (Ig) induced hemolytic response inside vessels leading to anemia and, thus, a cold antibody autoimmune hemolytic anemias (CAAHA). In 1865, it was widely accepted as a common sense that cold exposure may result in hemoglobinuria paroxysms. After decades of devoted researches, now the elucidation of the etiology and diagnostic methods of DLHA have been learned and developed.