Duct tape occlusion therapy (DTOT) is a method of treating warts by covering them with duct tape for prolonged periods. The manner in which duct tape appears to work is unclear. The tape might create a macerating and keratolytic environment, stimulating an immune response. The type of adhesive in the duct tape is likely to be important as leeching of the adhesive into the skin may be causing the immune system response. Side effects can include skin irritation and peeling.
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