Eastern North Carolina (sometimes abbreviated as ENC) is the region encompassing the eastern tier of North Carolina. It is known geographically as the state's Coastal Plain region. Primary subregions of Eastern North Carolina include the Sandhills, the Lower Cape Fear (Wilmington Area), the Crystal Coast, the Inner Banks and the Outer Banks. It is composed of the 41 most eastern counties in the state. Large cities include Greenville, Jacksonville, and Wilmington.