Edward Nicholas Crane (May 27, 1862 – September 20, 1896), nicknamed Cannonball, was an American right-handed pitcher and outfielder in Major League Baseball for eight seasons. He played for the Boston Reds (1884), Providence Grays (1885), Buffalo Bisons (1885), Washington Nationals (1886), New York Giants (NL) (1888–89, 1892–93), New York Giants (PL) (1890), Cincinnati Kelly's Killers (1891), Cincinnati Reds (1891), and Brooklyn Grooms (1893). Crane was the first pitcher in the history of major league baseball to record 4 strikeouts in a single inning (New York Giants, 1888), and is one of the few players to play in four major leagues: the Union Association, the National League, the Players' League, and the American Association.