The Edward Drinker Cope House is a historic house located at 2100–2102 Pine Street in Center City Philadelphia, Pennsylvania. Built in 1880, it was a longtime home of Edward Drinker Cope (1840–1897), a prolific geologist and paleontologist and noted herpetologist who was one of the leading natural scientists of the 19th century United States. It was declared a National Historic Landmark in 1975.