Ettore Pignatelli e Caraffa, 1st Duke of Monteleone, also spelled Carafa (Naples, Italy (died Palermo, Sicily, 1535), also known as Héctor Pignatelli, 1st Count of Monteleone since 1505, afterwards 1st Duke of Monteleone and Count of Borrello, was an Ambassador in Naples, Italy, of king Ferdinand II of Aragón (1453–1516), where his maternal half-sister Juana of Aragón was the young second Queen Consort of Naples, the 2nd wife of king Ferrante I of Naples.