• Facets (new session)
• Description
• Metadata
• Settings
  • Rule: ActivityStreamsMapasEquivalentb3sb3sifpdbprdf-labelfacetshttp://dbpedia.org/resource/inference/rules/dbpedia#http://dbpedia.org/resource/inference/rules/opencyc#http://dbpedia.org/resource/inference/rules/umbel#http://dbpedia.org/resource/inference/rules/yago#http://dbpedia.org/schema/property_rules#http://www.ontologyportal.org/inference/rules/SUMO#http://www.ontologyportal.org/inference/rules/WordNet#http://www.w3.org/2002/07/owl#ldpoplwebskos-transurn:det:rdf:labelvirtrdf-labelvirtrdf-urlNone
    
  • Inverse Functional Properties: Disabled (fastest) Apply to subjects only Apply to objects only Apply to both subjects and objects
  • "Same As": Disabled (fastest) Apply to subjects only Apply to objects only Apply to both subjects and objects (recommended) Apply to subjects, objects and predicates (not recommended on big datasets) Apply to predicates only (special use cases only)

About: Fura-2-acetoxymethyl ester     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : umbel-rc:ChemicalSubstanceType, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substanceChemical compoundyago:WikicatBenzofuransyago:WikicatBiochemistryMethodsyago:WikicatCarboxylateEstersyago:Ability105616246yago:AbsorptionIndicator114598383yago:Abstraction100002137yago:Benzofuran114898101yago:Chemical114806838yago:Cognition100023271yago:ColoringMaterial114984973yago:Compound114818238yago:Dye114985383yago:Element114840755yago:Ester114850483yago:Fluorescein114987695yago:Indicator114917208yago:Know-how105616786yago:Material114580897yago:Matter100020827yago:Method105660268yago:OrganicCompound114727670yago:Part113809207yago:PhysicalEntity100001930yago:PsychologicalFeature100023100yago:Quintessence114847103yago:Relation100031921chemical compoundyago:Substance100019613yago:WikicatAcetateEstersyago:WikicatFluorescentDyesyago:WikicatPhenolEthersumbel-rc:ChemicalSubstanceType New Facet based on Instances of this Class

Fura-2-acetoxymethyl ester, often abbreviated Fura-2AM, is a membrane-permeant derivative of the ratiometric calcium indicator Fura-2 used in biochemistry to measure cellular calcium concentrations by fluorescence. When added to cells, Fura-2AM crosses cell membranes and once inside the cell, the acetoxymethyl groups are removed by cellular esterases. Removal of the acetoxymethyl esters regenerates "Fura-2", the pentacarboxylate calcium indicator. Measurement of Ca2+-induced fluorescence at both 340 nm and 380 nm allows for calculation of calcium concentrations based 340/380 ratios. The use of the ratio automatically cancels out certain variables such as local differences in fura-2 concentration or cell thickness that would otherwise lead to artifacts when attempting to image calcium conce