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About: GABRA6     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:Transmission106251781, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: ThingBiomoleculegeneBiomoleculeGeneyago:Abstraction100002137yago:Act100030358yago:Channel106259898yago:Communication106252138yago:Event100029378yago:PsychologicalFeature100023100yago:WikicatIonChannelsyago:YagoPermanentlyLocatedEntityHumanGeneproteinyago:Transmission106251781 New Facet based on Instances of this Class

Gamma-aminobutyric acid receptor subunit alpha-6 is a protein that in humans is encoded by the GABRA6 gene. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. One study has found a genetic variant in the gene to be associated with the personality trait neuroticism.