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Ganirelix acetate (or diacetate), sold under the brand names Orgalutran and Antagon among others, is an injectable competitive gonadotropin-releasing hormone antagonist (GnRH antagonist). It is primarily used in assisted reproduction to control ovulation. The drug works by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of LH and FSH. Ganirelix is used in fertility treatment to prevent premature ovulation that could result in the harvesting of eggs that are too immature to be used in procedures such as in vitro fertilization.

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rdf:type
rdfs:label
  • Ganirelix (en)
  • Ganirelix (it)
rdfs:comment
  • Il ganirelix acetato (o diacetato) è un antagonista del GnRH selettivo dell'ormone di rilascio delle gonadotropine (GnRH) impiegato come trattamento farmacologico della riproduzione assistita per controllare l'ovulazione. Il farmaco agisce bloccando l'azione del GnRH sulla ipofisi, così rapidamente da sopprimere la produzione e l'azione degli ormoni LH e FSH. Il ganirelix è usato nel trattamento della infertilità per prevenire l'ovulazione prematura causata dalla raccolta di ovociti immaturi, per essere utilizzati nelle procedure di fecondazione in vitro. (it)
  • Ganirelix acetate (or diacetate), sold under the brand names Orgalutran and Antagon among others, is an injectable competitive gonadotropin-releasing hormone antagonist (GnRH antagonist). It is primarily used in assisted reproduction to control ovulation. The drug works by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of LH and FSH. Ganirelix is used in fertility treatment to prevent premature ovulation that could result in the harvesting of eggs that are too immature to be used in procedures such as in vitro fertilization. (en)
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  • http://commons.wikimedia.org/wiki/Special:FilePath/Ganirelix.svg
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ATC suffix
  • CC01 (en)
ATC prefix
  • H01 (en)
bioavailability
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class
DrugBank
  • DB06785 (en)
elimination half-life
excretion
  • Feces: 75% (en)
  • Urine: 22% (en)
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index2 label
  • as salt (en)
IUPAC name
KEGG
  • D04302 (en)
  • D08010 (en)
legal US
  • Rx-only (en)
n
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