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About: Gene isoform     Goto   Sponge   NotDistinct   Permalink

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Gene isoforms are mRNAs that are produced from the same locus but are different in their transcription start sites (TSSs), protein coding DNA sequences (CDSs) and/or untranslated regions (UTRs), potentially altering gene function. The gene isoforms can be sequenced by Whole Transcriptome Shotgun Sequencing (RNA-Seq). Recently some progress has been made to characterize known isoforms of regeneration associated genes (RAGs) using RNA-Seq, which is important in understanding the isoform diversity in the CNS.