About: Gene therapy for color blindness

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Gene therapy for color blindness is an experimental gene therapy of the human retina aiming to grant typical trichromatic color vision to individuals with congenital color blindness by introducing typical alleles for opsin genes. Animal testing for gene therapy began in 2007 with a 2009 breakthrough in squirrel monkeys suggesting an imminent gene therapy in humans. While the research into gene therapy for red-green colorblindness has lagged since then, successful human trials are ongoing for achromatopsia. Congenital color vision deficiency affects upwards of 200 million people in the world, which represents a large demand for this gene therapy.

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rdf:type	drug
rdfs:label	Gene therapy for color blindness (en) Thérapie génique pour le daltonisme (fr)
rdfs:comment	Gene therapy for color blindness is an experimental gene therapy of the human retina aiming to grant typical trichromatic color vision to individuals with congenital color blindness by introducing typical alleles for opsin genes. Animal testing for gene therapy began in 2007 with a 2009 breakthrough in squirrel monkeys suggesting an imminent gene therapy in humans. While the research into gene therapy for red-green colorblindness has lagged since then, successful human trials are ongoing for achromatopsia. Congenital color vision deficiency affects upwards of 200 million people in the world, which represents a large demand for this gene therapy. (en) La thérapie génique pour guérir le daltonisme est une thérapie génique expérimentale qui vise à convertir des individus daltoniens congénitaux en trichromates en introduisant le gène photopigmentaire qui leur manque. Même si le daltonisme partiel n'est considéré que comme un handicap léger, il s'agit d'une affection qui touche de nombreuses personnes, en particulier les hommes. Le daltonisme complet, ou achromatopsie, est très rare mais plus grave. Bien qu'il n'est jamais été démontré chez l'homme, des études animales ont montré qu'il est possible de conférer une vision des couleurs en injectant un gène du photopigment manquant grâce à la thérapie génique. (fr)
dct:subject	Genetic engineering Gene therapy Color vision
Wikipage page ID	27108706 (xsd:integer)
Wikipage revision ID	1110786895 (xsd:integer)
Link from a Wikipage to another Wikipage	David H. Hubel Designer babies Deuteranopia Allele House mouse Human brain Retina Visual acuity Voretigene neparvovec Intravitreal injection GNAT2 Nystagmus Scotopic vision Gene therapy Gene therapy of the human retina Opponent process Gerbils Cone cell Opsin Chimeric gene Color blindness Color vision Transgenic Visible spectrum Adeno-associated virus Torsten Wiesel Achromatopsia Genetic engineering ERG FMRI Visual cortex Gene therapy Jay Neitz CDNA Color vision Blue cone monochromacy Transduction (physiology) Squirrel monkey Green fluorescent protein Human eye New world monkeys Leber's congenital amaurosis Ocular dominance Visual phototransduction Trichromacy Photophobia Photopic vision Stem cell therapy for macular degeneration Electroretinogram Protanopia Tetrachromats Squirrel monkeys Neural circuitry Tritanopia
sameAs	Gene therapy for color blindness Gene therapy for color blindness Gene therapy for color blindness Gene therapy for color blindness
dbp:wikiPageUsesTemplate	dbt:Main_article dbt:Reflist
has abstract	Gene therapy for color blindness is an experimental gene therapy of the human retina aiming to grant typical trichromatic color vision to individuals with congenital color blindness by introducing typical alleles for opsin genes. Animal testing for gene therapy began in 2007 with a 2009 breakthrough in squirrel monkeys suggesting an imminent gene therapy in humans. While the research into gene therapy for red-green colorblindness has lagged since then, successful human trials are ongoing for achromatopsia. Congenital color vision deficiency affects upwards of 200 million people in the world, which represents a large demand for this gene therapy. (en) La thérapie génique pour guérir le daltonisme est une thérapie génique expérimentale qui vise à convertir des individus daltoniens congénitaux en trichromates en introduisant le gène photopigmentaire qui leur manque. Même si le daltonisme partiel n'est considéré que comme un handicap léger, il s'agit d'une affection qui touche de nombreuses personnes, en particulier les hommes. Le daltonisme complet, ou achromatopsie, est très rare mais plus grave. Bien qu'il n'est jamais été démontré chez l'homme, des études animales ont montré qu'il est possible de conférer une vision des couleurs en injectant un gène du photopigment manquant grâce à la thérapie génique. En 2018, aucune entité médicale n'offrait ce traitement et aucun essai clinique n'était disponible pour les volontaires. (fr)
gold:hypernym	Therapy
prov:wasDerivedFrom	wikipedia-en:Gene_therapy_for_color_blindness?oldid=1110786895&ns=0
page length (characters) of wiki page	18218 (xsd:nonNegativeInteger)
foaf:isPrimaryTopicOf	wikipedia-en:Gene_therapy_for_color_blindness
is Link from a Wikipage to another Wikipage of	Gene therapy of the human retina Congenital red–green color blindness Color blindness Macular degeneration Therapy List of therapies Stem cell therapy for macular degeneration
is foaf:primaryTopic of	wikipedia-en:Gene_therapy_for_color_blindness

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