German submarine U-1161 was a Type VIIC U-boat of Nazi Germany's Kriegsmarine during World War II. She was ordered on 25 August 1941, and was laid down on 27 October 1942 at Danziger Werft AG, Danzig, as yard number 133. She was launched on 8 May 1943 and commissioned under the command of Tenente di vascello Federico De Siervo on 25 August 1943.