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Gnotobiosis (from Greek roots gnostos "known" and bios "life") refers to an engineered state of an organism in which all forms of life (i.e., microorganisms) in or on it, including its microbiota, have been identified. The term gnotobiotic organism, or gnotobiote, can refer to a model organism that is colonized with a specific community of known microorganisms (isobiotic or defined flora animal) or that contains no microorganisms (germ-free) often for experimental purposes. The study of gnotobiosis and the generation of various types of gnotobiotic model organisms as tools for studying interactions between host organisms and microorganisms is referred to as gnotobiology.

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  • Gnotobiologie (cs)
  • Gnotobiose (de)
  • Gnotobionte (es)
  • Gnotobiosis (en)
  • Gnotobiose (fr)
  • Gnotobiologia (pt)
  • Гнотобиоз (ru)
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  • Gnotobiologie je nauka o bezmikrobních živočiších. Zabývá se živočichy získanými sterilními chirurgickými postupy nebo sterilním líhnutím z vajec. Tito živočichové jsou dále chováni ve sterilních izolovaných prostorách a krmeni sterilní potravou. Jsou buď zcela bezmikrobní, nebo jsou osazováni definovanými bakteriemi. Mezi živočichy, které gnotobiologie zkoumá, patří především prase, potkan, králík a různé kmeny myší. Na těchto modelech lze studovat vývoj přirozené a adaptivní imunity a vliv mikrobioty na příčiny a mechanismy vedoucí ke vzniku lidských chorob. (cs)
  • Gnotobiose (von den griechischen Wurzeln gnostos 'bekannt' und bios 'Leben') ist ein Zustand, bei dem alle in einem Organismus vorhandenen Lebensformen berücksichtigt werden können. Typischerweise sind gnotobiotische Organismen keimfrei oder gnotophor (mit nur einer Verunreinigung). (de)
  • Gnotobiosis (from Greek roots gnostos "known" and bios "life") refers to an engineered state of an organism in which all forms of life (i.e., microorganisms) in or on it, including its microbiota, have been identified. The term gnotobiotic organism, or gnotobiote, can refer to a model organism that is colonized with a specific community of known microorganisms (isobiotic or defined flora animal) or that contains no microorganisms (germ-free) often for experimental purposes. The study of gnotobiosis and the generation of various types of gnotobiotic model organisms as tools for studying interactions between host organisms and microorganisms is referred to as gnotobiology. (en)
  • La gnotobiose (du grec gnostos, "connu", et bios, "vie") est une condition dans laquelle, pour un organisme donné, toutes les formes de vie présentes au sein de cet organisme peuvent être comptabilisées. Les organismes gnotobiotiques sont typiquement exempts de micro-organismes ou gnotophoriques (ayant seulement un contaminant). (fr)
  • Gnotobiologia (do grego, γνώσις = gnōsis = saber; βίος = -bios, seres vivos; -λογος, -logia, estudo) ou ciência em animais limpos, é um ramo das ciências biológicas que trata dos animais de laboratórios como modelos e reagentes em pesquisa científica, levando em conta o seu particular e específico ambiente de organismos associados. O conhecimento, a manutenção e a transformação do status sanitário e ecológico dos animais para pesquisa é o principal objetivo desta ciência, cuja prática produz animais livres de germes ou, tendo sido associado a outros seres vivos, seguem tendo um status sanitário conhecido. (pt)
  • Гнотобио́з (от др.-греч. γνωτός [gnotos] — «известный» + «биос» как «жизнь») — биологический термин, означающий содержание лабораторных животных в научных целях в условиях стерильности или при наличии известных исследователям микроорганизмов. Обычно речь идёт об отсутствии микроорганизмов, живущих в и на животном. Такие животные могут быть рождены в асептических условиях, что может включать в себя кесарево сечение. (ru)
  • El término gnotobionte o gnotobiótico deriva de las palabras griegas "gnotos": conocimiento y "bio": vida. Significa "vida conocida".​ Se trata de un animal de experimentación portador de microflora y microfauna conocida y controlada, introducida tras nacimiento por cesárea en condiciones estériles. Estos animales son mantenidos en sistemas de aisladores, que han sido químicamente o físicamente esterilizados previo al uso. Igualmente el aire, el agua, el alimento y el encamado deben ser libres de gérmenes al entrar a los aisladores.​ (es)
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