The Great Fall River fire of 1928 occurred on February 2–3, 1928 and destroyed a vast portion of downtown Fall River, Massachusetts. Although the city has had many other large fires, both before and after, the 1928 conflagration is generally considered the worst in the city's history, since it destroyed so many businesses at a time when the city's economy was already struggling from recent textile plant closings. By the time the fire was out, five city blocks were completely wiped out. Nobody was killed and only a few people suffered serious injuries.