Guy R. Williams (October 7, 1907 – December 31, 1992) was a Canadian Senator and Haisla First Nations leader and was, for a number of years, the only Native Canadian in the Senate. He was appointed on December 9, 1971, following the March 31, 1971 retirement of James Gladstone who had been called the first status Indian appointed to the upper house. In fact Williams appears to be the very first First Nations Senator, because Senator Gladstone was only adopted onto the Blood reserve and he was ineligible to be on the Indian Register.