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About: Hippo signaling pathway     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:Series108457976, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: yago:WikicatAnimalGenesyago:Abstraction100002137yago:Arrangement107938773yago:Gene105436752yago:Group100031264yago:Ordering108456993yago:Sequence108459252yago:Series108457976 New Facet based on Instances of this Class

The Hippo signaling pathway, also known as the Salvador-Warts-Hippo (SWH) pathway, is a signaling pathway that controls organ size in animals through the regulation of cell proliferation and apoptosis. The pathway takes its name from one of its key signaling components—the protein kinase Hippo (Hpo). Mutations in this gene lead to tissue overgrowth, or a "hippopotamus"-like phenotype.