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Histrelin acetate, sold under the brand names Vantas and Supprelin LA among others, is a nonapeptide analogue of gonadotropin-releasing hormone (GnRH) with added potency. When present in the bloodstream, it acts on particular cells of the pituitary gland called gonadotropes. Histrelin stimulates these cells to release luteinizing hormone and follicle-stimulating hormone. Thus it is considered a gonadotropin-releasing hormone agonist or GnRH agonist.

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rdf:type
rdfs:label
  • Histrelin (en)
rdfs:comment
  • Histrelin acetate, sold under the brand names Vantas and Supprelin LA among others, is a nonapeptide analogue of gonadotropin-releasing hormone (GnRH) with added potency. When present in the bloodstream, it acts on particular cells of the pituitary gland called gonadotropes. Histrelin stimulates these cells to release luteinizing hormone and follicle-stimulating hormone. Thus it is considered a gonadotropin-releasing hormone agonist or GnRH agonist. (en)
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  • http://commons.wikimedia.org/wiki/Special:FilePath/Histrelin.svg
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sameAs
dbp:wikiPageUsesTemplate
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ATC suffix
  • AE05 (en)
ATC prefix
  • L02 (en)
bioavailability
c
CAS number
ChEMBL
ChemSpiderID
class
elimination half-life
H
IUPAC name
KEGG
  • D02369 (en)
legal US
  • Rx-only (en)
MedlinePlus
  • a601146 (en)
metabolism
n
O
pregnancy US
  • X (en)
PubChem
routes of administration
SMILES
  • CCNC[C@@H]1CCCN1C[C@H]NC[C@H]NC[C@@H]NC[C@H]NC[C@H]NC[C@H]NC[C@H]NC[C@@H]1CCCN1 (en)
StdInChI
StdInChIKey
  • HHXHVIJIIXKSOE-QILQGKCVSA-N (en)
tradename
  • Vantas, Supprelin LA, others (en)
UNII
  • H50H3S3W74 (en)
Verifiedfields
  • changed (en)
verifiedrevid
Watchedfields
  • changed (en)
width
has abstract
  • Histrelin acetate, sold under the brand names Vantas and Supprelin LA among others, is a nonapeptide analogue of gonadotropin-releasing hormone (GnRH) with added potency. When present in the bloodstream, it acts on particular cells of the pituitary gland called gonadotropes. Histrelin stimulates these cells to release luteinizing hormone and follicle-stimulating hormone. Thus it is considered a gonadotropin-releasing hormone agonist or GnRH agonist. (en)
IUPHAR ligand
protein bound
Bioavailability
gold:hypernym
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