Hlompho Kekana (born 23 May 1985) is a South African former professional soccer player who last played for Mamelodi Sundowns. He retired on 31 August 2021 after he was released by the team. On 4 March 2012, his team set a record in the Nedbank Cup when they beat Powerlines FC 24–0, with Kekana scoring seven of the goals. On 26 March 2016, while playing for the national team, Kekana scored on a shot from 65 yards against Cameroon. In 2016, he won the CAF Champions League with Mamelodi Sundowns as the club's captain.