A hyperintensity or T2 hyperintensity is an area of high intensity on types of magnetic resonance imaging (MRI) scans of the brain of a human or of another mammal that reflect lesions produced largely by demyelination and axonal loss. These small regions of high intensity are observed on T2 weighted MRI images (typically created using 3D FLAIR) within cerebral white matter (white matter lesions, white matter hyperintensities or WMH) or subcortical gray matter (gray matter hyperintensities or GMH). The volume and frequency is strongly associated with increasing age. They are also seen in a number of neurological disorders and psychiatric illnesses. For example, deep white matter hyperintensites are 2.5 to 3 times more likely to occur in bipolar disorder and major depressive disorder than co
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| - Hyperintensity (en)
- Hyperintensitet (sv)
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| - A hyperintensity or T2 hyperintensity is an area of high intensity on types of magnetic resonance imaging (MRI) scans of the brain of a human or of another mammal that reflect lesions produced largely by demyelination and axonal loss. These small regions of high intensity are observed on T2 weighted MRI images (typically created using 3D FLAIR) within cerebral white matter (white matter lesions, white matter hyperintensities or WMH) or subcortical gray matter (gray matter hyperintensities or GMH). The volume and frequency is strongly associated with increasing age. They are also seen in a number of neurological disorders and psychiatric illnesses. For example, deep white matter hyperintensites are 2.5 to 3 times more likely to occur in bipolar disorder and major depressive disorder than co (en)
- Med hyperintensitet avses ett område i hjärnan som uppvisar hög intensitet vid vissa sorters magnetkameraundersökningar, så kallade MRI. Dessa små områden med hög intensitet kan uppstå naturligt till följd av åldrande men uppstår även i samband med en rad mentala åkommor, till exempel är hyperintesitet mellan 2,5 och 3 gånger vanligare hos personer som lider av bipolär sjukdom. Hyperintensitet visar sig i form av ljusa fläckar på bilderna från MRI. Hyperintensitet delas vanligen in i tre olika typer beroende på var i hjärnan förändringen uppstår. (sv)
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| - A hyperintensity or T2 hyperintensity is an area of high intensity on types of magnetic resonance imaging (MRI) scans of the brain of a human or of another mammal that reflect lesions produced largely by demyelination and axonal loss. These small regions of high intensity are observed on T2 weighted MRI images (typically created using 3D FLAIR) within cerebral white matter (white matter lesions, white matter hyperintensities or WMH) or subcortical gray matter (gray matter hyperintensities or GMH). The volume and frequency is strongly associated with increasing age. They are also seen in a number of neurological disorders and psychiatric illnesses. For example, deep white matter hyperintensites are 2.5 to 3 times more likely to occur in bipolar disorder and major depressive disorder than control subjects. WMH volume, calculated as a potential diagnostic measure, has been shown to correlate to certain cognitive factors. Hyperintensities appear as "bright signals" (bright areas) on an MRI image and the term "bright signal" is occasionally used as a synonym for a hyperintensity. Hyperintensities are commonly divided into 3 types depending on the region of the brain where they are found. Deep white matter hyperintensites occur deep within white matter, periventricular white matter hyperintensities occur adjacent to the lateral ventricles and subcortical hyperintensities occur in the basal ganglia. Hyperintensities are often seen in auto immune diseases that have effects on the brain. Postmortem studies combined with MRI suggest that hyperintensities are dilated perivascular spaces, or demyelination caused by reduced local blood flow. (en)
- Med hyperintensitet avses ett område i hjärnan som uppvisar hög intensitet vid vissa sorters magnetkameraundersökningar, så kallade MRI. Dessa små områden med hög intensitet kan uppstå naturligt till följd av åldrande men uppstår även i samband med en rad mentala åkommor, till exempel är hyperintesitet mellan 2,5 och 3 gånger vanligare hos personer som lider av bipolär sjukdom. Hyperintensitet visar sig i form av ljusa fläckar på bilderna från MRI. Hyperintensitet delas vanligen in i tre olika typer beroende på var i hjärnan förändringen uppstår. Forskning som bedrivits genom obduktioner i kombination med MRI visar på att hyperintensitet är utrymmen som uppstår till följd av ett lokalt reducerat blodflöde. (sv)
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