Infectious canine hepatitis (ICH) is an acute liver infection in dogs caused by Canine mastadenovirus A, formerly called Canine adenovirus 1 (CAV-1). CAV-1 also causes disease in wolves, coyotes, and bears, and encephalitis in foxes. The virus is spread in the feces, urine, blood, saliva, and nasal discharge of infected dogs. It is contracted through the mouth or nose, where it replicates in the tonsils. The virus then infects the liver and kidneys. The incubation period is 4 to 9 days.
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| - Hepatitis contagiosa canis (de)
- Canine mastadenovirus A (in)
- Hépatite de Rubarth (fr)
- Infectious canine hepatitis (en)
- Epatite infettiva del cane (it)
- 犬伝染性肝炎 (ja)
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| - Die Hepatitis contagiosa canis (Hcc; Syn: „Ansteckende Leberentzündung der Hunde“, Rubarth-Krankheit, Fuchsenzephalitis, infectious canine hepatitis (ICH)) ist eine durch ein Virus hervorgerufene Leberentzündung der Hunde. Insgesamt wird die Erkrankung – als Folge wirksamer und umfassender Impfmaßnahmen – heute nur noch selten beobachtet. (de)
- Canine mastadenovirus A adalah spesies virus dalam genus dan famili Adenoviridae yang mengakibatkan hepatitis anjing infeksius. Takson ini sebelumnya bernama Canine adenovirus (CAV), yang pada 2013 diubah namanya menjadi Canine mastadenovirus A oleh Komite Internasional Taksonomi Virus (ICTV). (in)
- L'epatite infettiva del cane è un'infezione epatica acuta dei canidi causata da adenovirus canino di tipo 1 (CAV-1). Il CAV-1 è causa di patologia anche nei lupi, coyote, gli orsi e nella volpe. (it)
- L'hépatite de Rubarth, encore appelée maladie de Rubarth, hépatite contagieuse canine ou adénovirose canine, est une affection contagieuse et virulente du chien, également observée chez le renard, le loup, le coyote, l'ours, le lynx et chez certains pinnipèdes. Dans les pays où les propriétaires d'animaux de compagnie ont adopté la prévention vaccinale, la maladie passe le plus souvent inaperçue. Lorsqu'elle se déclare, elle s'exprime surtout chez les jeunes sujets, où elle se manifeste par des symptômes digestifs et oculaires. (fr)
- 犬伝染性肝炎（いぬでんせんせいかんえん、英:infectious canine hepatitis）とは、アデノウイルス科に属する犬アデノウイルス1感染を原因とするイヌ科動物の感染症。感染動物の糞尿、唾液を介して経口、経鼻的に感染が成立する。 1歳以下の犬では致死率が高いが、成犬では不顕性感染を示すことが多い。症状として発熱、下痢、嘔吐、腹痛などを示し、肝臓の腫脹が認められる。組織学的には肝実質の壊死巣、肝細胞や血管内皮細胞内の核内封入体が認められる。20%前後の個体で臨床症状が消失した後にブルーアイが観察される。治療には対症療法を行う。予防には弱毒生ワクチンが用いられる。 (ja)
- Infectious canine hepatitis (ICH) is an acute liver infection in dogs caused by Canine mastadenovirus A, formerly called Canine adenovirus 1 (CAV-1). CAV-1 also causes disease in wolves, coyotes, and bears, and encephalitis in foxes. The virus is spread in the feces, urine, blood, saliva, and nasal discharge of infected dogs. It is contracted through the mouth or nose, where it replicates in the tonsils. The virus then infects the liver and kidneys. The incubation period is 4 to 9 days. (en)
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| - Canine mastadenovirus A (en)
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| - * Canine adenovirus A
* Canine adenovirus
* Canine adenovirus 1
* Canine adenovirus 2 (en)
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| - Die Hepatitis contagiosa canis (Hcc; Syn: „Ansteckende Leberentzündung der Hunde“, Rubarth-Krankheit, Fuchsenzephalitis, infectious canine hepatitis (ICH)) ist eine durch ein Virus hervorgerufene Leberentzündung der Hunde. Insgesamt wird die Erkrankung – als Folge wirksamer und umfassender Impfmaßnahmen – heute nur noch selten beobachtet. (de)
- Infectious canine hepatitis (ICH) is an acute liver infection in dogs caused by Canine mastadenovirus A, formerly called Canine adenovirus 1 (CAV-1). CAV-1 also causes disease in wolves, coyotes, and bears, and encephalitis in foxes. The virus is spread in the feces, urine, blood, saliva, and nasal discharge of infected dogs. It is contracted through the mouth or nose, where it replicates in the tonsils. The virus then infects the liver and kidneys. The incubation period is 4 to 9 days. Symptoms include fever, depression, loss of appetite, coughing, and a tender abdomen. Corneal edema and signs of liver disease, such as jaundice, vomiting, and hepatic encephalopathy, may also occur. Severe cases will develop bleeding disorders, which can cause hematomas to form in the mouth. Death can occur secondary to this or the liver disease. However, most dogs recover after a brief illness, although chronic corneal edema and kidney lesions may persist. Diagnosis is made by recognizing the combination of symptoms and abnormal blood tests that occur in infectious canine hepatitis. A rising antibody titer to CAV-1 is also seen. The disease can be confused with canine parvovirus because both will cause a low white blood cell count and bloody diarrhea in young, unvaccinated dogs. Treatment is symptomatic. Most dogs recover spontaneously without treatment. Prevention is through vaccination (ATCvet code QI07AA05 (WHO) and various combination vaccines). Most combination vaccines for dogs contain a modified canine adenovirus type-2. CAV-2 is one of the causes of respiratory infections in dogs, but it is similar enough to CAV-1 that vaccine for one creates immunity for both. CAV-2 vaccine is much less likely to cause side effects than CAV-1 vaccine. One study has shown the vaccine to have a duration of immunity of at least four years. CAV-1 is destroyed in the environment by steam cleaning and quaternary ammonium compounds. Otherwise, the virus can survive in the environment for months in the right conditions. It can also be released in the urine of a recovered dog for up to a year. (en)
- Canine mastadenovirus A adalah spesies virus dalam genus dan famili Adenoviridae yang mengakibatkan hepatitis anjing infeksius. Takson ini sebelumnya bernama Canine adenovirus (CAV), yang pada 2013 diubah namanya menjadi Canine mastadenovirus A oleh Komite Internasional Taksonomi Virus (ICTV). (in)
- L'epatite infettiva del cane è un'infezione epatica acuta dei canidi causata da adenovirus canino di tipo 1 (CAV-1). Il CAV-1 è causa di patologia anche nei lupi, coyote, gli orsi e nella volpe. (it)
- L'hépatite de Rubarth, encore appelée maladie de Rubarth, hépatite contagieuse canine ou adénovirose canine, est une affection contagieuse et virulente du chien, également observée chez le renard, le loup, le coyote, l'ours, le lynx et chez certains pinnipèdes. Dans les pays où les propriétaires d'animaux de compagnie ont adopté la prévention vaccinale, la maladie passe le plus souvent inaperçue. Lorsqu'elle se déclare, elle s'exprime surtout chez les jeunes sujets, où elle se manifeste par des symptômes digestifs et oculaires. (fr)
- 犬伝染性肝炎（いぬでんせんせいかんえん、英:infectious canine hepatitis）とは、アデノウイルス科に属する犬アデノウイルス1感染を原因とするイヌ科動物の感染症。感染動物の糞尿、唾液を介して経口、経鼻的に感染が成立する。 1歳以下の犬では致死率が高いが、成犬では不顕性感染を示すことが多い。症状として発熱、下痢、嘔吐、腹痛などを示し、肝臓の腫脹が認められる。組織学的には肝実質の壊死巣、肝細胞や血管内皮細胞内の核内封入体が認められる。20%前後の個体で臨床症状が消失した後にブルーアイが観察される。治療には対症療法を行う。予防には弱毒生ワクチンが用いられる。 (ja)
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