Inositol trisphosphate receptor (InsP3R) is a membrane glycoprotein complex acting as a Ca2+ channel activated by inositol trisphosphate (InsP3). InsP3R is very diverse among organisms, and is necessary for the control of cellular and physiological processes including cell division, cell proliferation, apoptosis, fertilization, development, behavior, learning and memory. Inositol triphosphate receptor represents a dominant second messenger leading to the release of Ca2+ from intracellular store sites. There is strong evidence suggesting that the InsP3R plays an important role in the conversion of external stimuli to intracellular Ca2+ signals characterized by complex patterns relative to both space and time, such as Ca2+ waves and oscillations.
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| - IP3-Rezeptor (de)
- Récepteur de l'inositol trisphosphate (fr)
- Inositol trisphosphate receptor (en)
- Recettore dell'inositolo trifosfato (it)
- イノシトールトリスリン酸受容体 (ja)
- IP3-receptor (nl)
- Receptor de inositol trifosfato (pt)
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| rdfs:comment
| - Der IP3-Rezeptor ist ein ligandenaktivierter Calciumkanal in der Membran des glatten endoplasmatischen Retikulums (ER). Sein spezifischer Ligand ist das Inositoltrisphosphat (abgekürzt IP3). (de)
- Inositol trisphosphate receptor (InsP3R) is a membrane glycoprotein complex acting as a Ca2+ channel activated by inositol trisphosphate (InsP3). InsP3R is very diverse among organisms, and is necessary for the control of cellular and physiological processes including cell division, cell proliferation, apoptosis, fertilization, development, behavior, learning and memory. Inositol triphosphate receptor represents a dominant second messenger leading to the release of Ca2+ from intracellular store sites. There is strong evidence suggesting that the InsP3R plays an important role in the conversion of external stimuli to intracellular Ca2+ signals characterized by complex patterns relative to both space and time, such as Ca2+ waves and oscillations. (en)
- Le récepteur de l'inositol trisphophate est une protéine ayant le rôle de récepteur et de canal ionique, situé sur le réticulum endoplasmique et intervenant dans le relargage des ions calcium. Son activité est régulée par l'inositol trisphosphate mais aussi par les ions calcium. (fr)
- イノシトールトリスリン酸受容体（イノシトールトリスリンさんじゅようたい、英：Inositol trisphosphate receptor、IP3R、IP3受容体）はイノシトールトリスリン酸 (IP3) により活性化される、カルシウムチャネルの働きをする膜糖タンパク質群である。IP3受容体はネズミの小脳から最初に精製された。 (ja)
- De inositoltrifosfaatreceptor (IP3-receptor of InsP3R) is een calciumkanaal dat vooral voorkomt in het membraan van het endoplasmatisch reticulum van cellen in het cerebellum. Het is genoemd naar de stof , die in staat is dit kanaal te activeren. De IP3-receptor is verwant aan de ryanodinereceptor, die vooral voorkomt in spiercellen. (nl)
- Il Recettore dell'inositolo trifosfato è un recettore costituito da un complesso glicoproteico che funge da canale del calcio. Una volta che l'inositolo trifosfato si lega al recettore, questo si apre favorendo il flusso di ioni calcio. (it)
- O receptor de inositol trifosfato (IP3R) é um complexo membranar glicoproteico que actua como activado por inositol trifosfato (IP3). O receptor de IP3 foi purificado pela primeira vez a partir de cerebelo de rato. (pt)
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| - inositol 1,4,5-trisphosphate receptor, type 1 (en)
- inositol 1,4,5-trisphosphate receptor, type 2 (en)
- inositol 1,4,5-trisphosphate receptor, type 3 (en)
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