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About: Integrative and conjugative element     Goto   Sponge   NotDistinct   Permalink

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Integrative and conjugative elements (ICEs) are mobile genetic elements present in both gram-positive and gram-negative bacteria. In a donor cell, ICEs are located primarily on the chromosome, but have the ability to excise themselves from the genome and transfer to recipient cells via bacterial conjugation. Due to their physical association with chromosomes, identifying integrative and conjugative elements has proven challenging, but in silico analysis of bacterial genomes indicate these elements are widespread among many microorganisms.